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Thermo Scientific Chemicals 2',3'-Dideoxicitidina + 98 %

Código de producto. 11322906
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Código de producto. 11322906 Proveedor Thermo Scientific Chemicals N.º de proveedor L10619.MF
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CAS: 7481-89-2 | C9H13N3O3 | 211.22 g/mol

2',3'-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered. It is also is used as a DNA chain-terminating nucleotide for DNA sequencing methods based on the Sanger chain-termination method.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 7481-89-2
Fórmula molecular C9H13N3O3
Peso molecular (g/mol) 211.22
Número MDL MFCD00012188
Clave InChI WREGKURFCTUGRC-KGQMAECUNA-N
Sinónimo zalcitabine, 2',3'-dideoxycytidine, dideoxycytidine, ddcyd, hivid, ddc, cytidine, 2',3'-dideoxy, zalcitibine, ddc antiviral, 4-amino-1-2r,5s-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidin-2 1h-one
PubChem CID 24066
ChEBI CHEBI:10101
SMILES NC1=NC(=O)N(C=C1)[C@H]1CC[C@@H](CO)O1

Specifications

Nombre del producto químico o material 2′,3′-Dideoxycytidine
Punto de fusión 216°C to 220°C
Envase Frasco de vidrio
Cantidad 50 mg
Beilstein 654956
Información de solubilidad Soluble in water (76.4mg/ml at 25°C),DMSO (42mg/ml at 25°C),and ethanol (<1mg/ml at 25°C).
Nombre IUPAC 4-amino-1-[(2R,5S)-5-(hidroximetil)oxolan-2-il]pirimidin-2-ona
Formula Weight (peso de la fórmula) 211.22
Porcentaje de pureza ≥98%
Forma física Sólido
compliance-icons
Product Identifier
  • 2',3'-Dideoxycytidine
Signal Word
  • Atención
Hazard Category
  • Carcinogenicidad Categoría 2
Hazard Statement
  • H351-Se sospecha que provoca cáncer.
Precautionary Statement
  • P201-Pedir instrucciones especiales antes del uso.
  • P280-Llevar guantes/prendas/gafas/máscara de protección.
  • P308+P313-EN CASO DE exposición manifiesta o presunta: Consultar a un médico.
Supplemental information
  • MIXTURE LIST-Contém: 2,3-Dideoxycytidine

RUO – Research Use Only

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