CAS RN 874819-74-6

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Fosfato de toceranib, TRC

CAS: 874819-74-6 Fórmula molecular: C22H25FN4O2 . H3PO4 Peso molecular (g/mol): 494.5 Sinónimo: PHA 291639E,5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrrole-3-carboxamide Phosphate Nombre IUPAC: 5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ilideno)metil]-2,4-dimetil-N-(2-pirrolidina-1-iletil)-1H-pirol-3-carboxamida; Ácido fosfórico SMILES: Cc1[nH]c(\C=C\2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NCCN4CCCC4.OP(=O)(O)O

Precio y disponibilidad
Especificaciones

Sinónimo	PHA 291639E,5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrrole-3-carboxamide Phosphate
Fórmula molecular	C22H25FN4O2 . H3PO4
CAS	874819-74-6
Peso molecular (g/mol)	494.5
SMILES	Cc1[nH]c(\C=C\2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NCCN4CCCC4.OP(=O)(O)O
Nombre IUPAC	5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ilideno)metil]-2,4-dimetil-N-(2-pirrolidina-1-iletil)-1H-pirol-3-carboxamida; Ácido fosfórico

Toceranib phosphate, MedChemExpress

MedChemExpress Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors .

Precio y disponibilidad
Especificaciones

Sinónimo	SU11654 phosphatePHA 291639E phosphate
Información de solubilidad	DMSO : 2.46 mg/mL (4.98 mM; Need ultrasonic and warming) ∣H2O : < 0.1 mg/mL (insoluble)
Forma física	Solid
Almacenamiento recomendado	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Color	Naranja
SMILES	O=C(NCCN1CCCC1)C2=C(NC(/C=C3C(NC4=C\3C=C(C=C4)F)=O)=C2C)C.O=P(O)(O)O
Notas de grado de pureza	Research
Duración de almacenamiento	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Formula Weight (peso de la fórmula)	494.45
Fórmula molecular	C₂₂H₂₈FN₄O₆P
CAS	874819-74-6
Nombre del producto químico o material	Toceranib phosphate
Porcentaje de pureza	98.02%
Peso molecular (g/mol)	494.45
Grado	Research
Para utilizar con (aplicación)	Cancer-Kinase/protease

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