CAS RN 1952251-28-3

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TAK-659 hydrochloride, MedChemExpress

MedChemExpress TAK-659 hydrochloride is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively. TAK-659 hydrochloride induces cell death in tumor cells but not in nontumor cells, and with potential for the treatment of chronic lymphocytic leukemia (CLL).

Precio y disponibilidad
Especificaciones

Información de solubilidad	H2O : 2 mg/mL (5.25 mM; ultrasonic and adjust pH to 3 with HCl) ∣DMSO : < 1 mg/mL (insoluble or slightly soluble)
Forma física	Solid
Almacenamiento recomendado	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Color	Blanco
SMILES	FC1=C(N[C@@H]2CCCC[C@@H]2N)N=C(C3=CN(C)N=C3)C4=C1CNC4=O.Cl
Notas de grado de pureza	Research
Duración de almacenamiento	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Formula Weight (peso de la fórmula)	380.85
Fórmula molecular	C₁₇H₂₂ClFN₆O
CAS	1952251-28-3
Nombre del producto químico o material	TAK-659 hydrochloride
Porcentaje de pureza	98.13%
Peso molecular (g/mol)	380.85
Grado	Research
Para utilizar con (aplicación)	Cancer-Kinase/protease

CAS RN 1952251-28-3

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