CAS RN 1380575-43-8

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Ceritinib dihydrochloride, MedChemExpress

MedChemExpress Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib dihydrochloride (LDK378 dihydrochloride) also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib dihydrochloride (LDK378 dihydrochloride) shows great antitumor potency.

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Especificaciones

Sinónimo	LDK378 dihydrochloride
Información de solubilidad	DMSO : 100 mg/mL (158.46 mM; Need ultrasonic) ∣H2O : 10 mg/mL (15.85 mM; Need ultrasonic)
Forma física	Solid
Almacenamiento recomendado	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Color	Light Yellow
SMILES	CC(C)OC1=CC(C2CCNCC2)=C(C)C=C1NC3=NC=C(Cl)C(NC4=CC=CC=C4S(=O)(C(C)C)=O)=N3.[H]Cl.[H]Cl
Notas de grado de pureza	Research
Duración de almacenamiento	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Formula Weight (peso de la fórmula)	631.06
Fórmula molecular	C₂₈H₃₈Cl₃N₅O₃S
CAS	1380575-43-8
Nombre del producto químico o material	Ceritinib dihydrochloride
Porcentaje de pureza	99.0%
Peso molecular (g/mol)	631.06
Grado	Research
Para utilizar con (aplicación)	Cancer-Kinase/protease

CAS RN 1380575-43-8

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