CAS RN 1346233-68-8
IUPAC Nombre:
3,5-dichloro-N-{[3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl}benzamide hydrochloride
Sinónimos:
3,5-dichloro-N-{[3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl}benzamide hydrochloride
Peso molecular (g/mol):
405.79
Fórmula molecular:
C19H27Cl3N2O
InChi Key:
IDCVEUISZZKMKJ-UHFFFAOYNA-N
SMILES:
Cl.CC(C)(C)CCN1CC2C(CNC(=O)C3=CC(Cl)=CC(Cl)=C3)C2C1
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ML218, MedChemExpress
MedChemExpress ML218 is a potent, selective and orally active T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3) inhibitor with IC50s of 310 nM and 270 nM for Cav3.2 and Cav3.3, respectively. ML218 inhibits the burst activity in subthalamic nucleus (STN) neurons. ML218 has no significant inhibition of L- or N-type calcium channels, KATP or hERG potassium channels. ML218 can penetrate the blood-brain barrier.
