CAS RN 1310726-60-3
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Tocris Bioscience™ Upadacitinib
JAK1-selective inhibitor
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Upadacitinib, MedChemExpress
MedChemExpress Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) can be used for several autoimmune disorders research.
