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Description
10883-1-AP reacts with p16 specifically. P16 plays an essential role in regulating the cell cycle, and mutations in p16 increase the risk of developing various cancers, including melanoma.
Kaiso is a novel member of the BTB/POZ (Broad complex, Tramtrak, Bric a brac/Pox virus and zinc finger) zinc finger superfamily of transcription factors. Yeast 2-hybrid studies have shown that Kaiso interacts with catenin p120ctn. This interaction involves the Arm repeats of 1-7 of the p120ctn Armadillo domain and the carboxyl-terminal third of Kaiso. The significance of the Kaiso:p120 ctn interaction is still unknown.
Specifications
Specifications
| Antigen | P16-INK4A |
| Applications | Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence |
| Classification | Polyclonal |
| Concentration | 0.37 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gene | CDKN2A |
| Gene Accession No. | Q8N726 |
| Gene Alias | ARF, ARF,CDKN2A, CDK4 inhibitor p16 INK4, CDK4 inhibitor p16INK4, CDK4I, CDKN2, CDKN2A, CMM2, INK4, INK4a, MLM, MTS 1, MTS1, Multiple tumor suppressor 1, P16, p16 INK4, p16 INK4a, p16INK4, p16INK4a, TP16 |
| Gene Symbols | CDKN2A |
| Show More |
Product Title
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