CAS RN 937174-76-0
IUPAC Nombre:
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(piperidin-3-yl)methoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
Sinónimos:
4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
Peso molecular (g/mol):
425.49
Fórmula molecular:
C21H27N7O3
InChi Key:
KGPGFQWBCSZGEL-UHFFFAOYNA-N
SMILES:
CCN1C(=NC2=C(N=CC(OCC3CCCNC3)=C12)C#CC(C)(C)O)C1=NON=C1N
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GSK-690693, MedChemExpress
MedChemExpress GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation.
