CAS RN 827022-33-3
IUPAC Nombre:
2-hydroxyethane-1-sulfonic acid; 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one
Sinónimos:
isethionic acid; palbociclib
Peso molecular (g/mol):
573.67
Fórmula molecular:
C26H35N7O6S
InChi Key:
LYYVFHRFIJKPOV-UHFFFAOYSA-N
SMILES:
OCCS(O)(=O)=O.CC(=O)C1=C(C)C2=CN=C(NC3=NC=C(C=C3)N3CCNCC3)N=C2N(C2CCCC2)C1=O
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1
Tocris Bioscience™ PD 0332991 isethionate
CAS: 827022-33-3 Fórmula molecular: C26H35N7O6S
2
Palbociclib isethionate, MedChemExpress
MedChemExpress Palbociclib (PD 0332991) isethionate is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib isethionate has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.
