CAS RN 1613695-14-9
IUPAC Nombre:
2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)propyl]-1H-1,3-benzodiazole
Sinónimos:
2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)propyl]-1,3-benzodiazole
Peso molecular (g/mol):
509.05
Fórmula molecular:
C28H33ClN4O3
InChi Key:
GEPYBHCJBORHCE-UHFFFAOYNA-N
SMILES:
COC1=C(Cl)C=C(CCC2=NC3=CC(=CC=C3N2CC(C)N2CCOCC2)C2=C(C)ON=C2C)C=C1
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Tocris Bioscience™ SGC-CBP30
CAS: 1613695-14-9 Fórmula molecular: C28H33ClN4O3
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SGC-CBP30, MedChemExpress
MedChemExpress SGC-CBP30 is a potent and highly selective CBP/p300 bromodomain (Kds of 21 nM and 32 nM for CBP and p300, respectively) inhibitor, displaying 40-fold selectivity over the first bromodomain of BRD4 [BRD4(1)] bound. SGC-CBP30 strongly reduces secretion of IL-17A in Th17 cells and has anti-inflammatory effects.
