CAS RN 1430208-73-3
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Tocris Bioscience™ 1A-116
Rac1 inhibitor; blocks Rac1-P-Rex1 interaction
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1A-116, MedChemExpress
MedChemExpress 1A-116, a potent Rac1 inhibitor, is specific for W56 residues, can prevent EGF-induced Rac1 activation and block Rac1-P-Rex1 interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo.