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Torsin A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 10296-1-AP-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16816593

  • 140.00€ / 20 microlitros
Fecha estimada de envío: 04-04-2024
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Descripción

Descripción

A mutation of the DYT1 gene, which codes for TorsinA, has been identified as the cause of one form of autosomal domitly inherited dystonia. Early-onset torsion dystonia is a movement disorder, characterized by twisting muscle contractures, that begins in childhood. Symptoms are believed to result from altered neuronal communication in the basal ganglia. TorsinA comprises 332 amino acids. TorsinA is widely expressed throughout the mouse central nervous system and is detected in the majority of neurons in nearly all regions. The proteins display cytoplasmic distribution, although in some types of neurons localization is perinuclear. TorsinA often performs chaperone-like functions that assist in the assembly, operation, or dis-assembly of protein complexes. The gene which encodes TorsinA has high homology to three additional mammalian genes and a nematode gene and distal similarity to the family of heat-shock proteins and the Clp protease family. The gene which encodes TorsinA maps to human chromosome 9q34.
Especificaciones

Especificaciones

Torsin A
Polyclonal
Unconjugated
TOR1A
DQ2, Dystonia 1 protein, DYT1, TOR1A, Torsin 1A, Torsin A, Torsin family 1 member A, TorsinA
Rabbit
Antigen Affinity Chromatography
RUO
1861, 266606, 30931
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.26 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O14656, Q68G38, Q9ER39
TOR1A
Torsin A Fusion Protein Ag0358
20 μL
Primary
Rat, Human, Mouse
Antibody
IgG
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