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Topoisomerase II α Ab-1, Rabbit Polyclonal Antibody,Lab Vision™ Epredia™
Provide accurate, reproducible results with the Epredia™ Topoisomerase II α Ab-1, Rabbit Polyclonal Antibody.
Marca: Epredia RB-117-P1
Detalles adicionales : Peso : 1.00000kg
Descripción
Topo IIα plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Note that Ki67/M1B1 is also present in G1-phase. Topo IIα is also implicated in drug resistance of tumor cells.Host Species: Rabbit
Isotype: IgG
Species Reactivity: Human. Others not known.
Epitope: aa 1513-1530
Immunogen: A synthetic peptide, corresponding to aa 1513-1530 (RAKKPIKYLEESDEDDLF) from the C-terminus of human topoisomerase IIα
Molecular Weight: 170kDa
Positive Control: Raji cells or any exponentially growing cultured human cells
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry
- Western Blotting
- Immunofluorescence
- Immunoprecipitation (Native and denatured)
Note:
USA: RUO; Int'l: RUO
Especificaciones
| Topoisomerase II alpha Ab-1 | |
| Polyclonal | |
| Unconjugated | |
| A synthetic peptide, corresponding to aa 1513-1530 (RAKKPIKYLEESDEDDLF) from the C-terminus of human topoisomerase IIalpha | |
| RUO | |
| Primary | |
| Concentrated |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 1mg/mL | |
| Rabbit | |
| 500 μL | |
| DNA Repair | |
| Human | |
| IgG |