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TNF Rat anti-Mouse, PE-Cy7, Clone: MP6-XT22, BD

Rat Monoclonal Antibody

230.00€ - 601.00€

Especificaciones

Antígeno TNF
Clon MP6-XT22
Concentración 0.2mg/mL
Aplicaciones Flow Cytometry
Clasificación Monoclonal
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
15890709
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BD Biosciences
561041
25 μg
230.00€
cada uno
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»
Fecha estimada de envío: 05-08-2024
para ver el stock
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12683356
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BD Biosciences
557644
0.1 mg
601.00€
cada uno
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Ahorre hasta 
»
Fecha estimada de envío: 05-08-2024
para ver el stock
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

The MP6-XT22 antibody specifically binds to mouse Tumor Necrosis Factor (TNF, also known as TNF-α). TNF is produced by many activated cell types including monocytes, macrophages, astrocytes, granulocytes, mast cells, T and B lymphocytes, NK cells, keratinocytes, fibroblasts, adipocytes, and certain tumor cells. Activated cells express type II transmembrane TNF glycoproteins that associate as homotrimeric complexes. After enzymatic cleavage, the extracellular regions of membrane TNF are shed as soluble homotrimers. TNF is a potent multifunctional cytokine that can exert regulatory and cytotoxic effects on a wide range of normal lymphoid and non-lymphoid cells and tumor cells. Although TNF serves as a primary mediator in protective immune responses against microbial and viral pathogens, it can also drive systemic pathophysiologic responses including septic shock, cachexia and autoimmune diseases. Mouse TNF exerts its biological activities by binding and signaling through cell surface membrane Type I and Type II TNF Receptors (aka, TNFRI/CD120a and TNFRII/CD120b, respectively).

Especificaciones

Especificaciones

TNF
0.2mg/mL
Monoclonal
Rat
Mouse
Recombinant Mouse TNF
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
MP6-XT22
Flow Cytometry
PE-Cyanine7
RUO
Aqueous buffered solution containing ≤0.09% sodium azide.
IgG1
Affinity Purified
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SDS
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Product Certifications

For Research Use Only.