Invitrogen™ Human TLR6 Synthetic Peptide

Descripción

TLR6 Synthetic Peptide, PEP-0317, from Invitrogen.

TLR6 (Toll-like receptor 6) is a member of the toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved and share structural and functional similarities. TLRs recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR6 functionally interacts with TLR2 to mediate cellular response to bacterial lipoproteins. This peptide corresponds to 15 amino acids near the amino terminus of human TLR6.PEP-0317 can be used as a blocking peptide with polyclonal antibody PA5-20187.