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Invitrogen™ Human Thioredoxin 1, Recombinant Protein

Recombinant Protein

Marca:  Invitrogen™ LFP0001

Detalles adicionales : Peso : 0.99000kg

Código de producto. 10130860

  • 265.00€ / 10 unidades
Fecha estimada de envío: 25-04-2024
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Descripción

Descripción

Thioredoxin 1 Recombinant Protein, LF-P0001, from Invitrogen.

Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductaseactivity and are ubiquitous in essentially all living cells. Trx contains aredox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cysactive site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and apotent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide -isomerase (PDI) and anumber of transcription factors such as p53 , NF-kB and AP-1 (T1-151). Trx is also capable of removing H2O2, particularly when it iscoupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins. This protein corresponds to human Thioredoxin 1 (1-105 aa), which has a molecular weight of 11.7 kDa. Specific activity: 8.15 U/mg, where one unit will cause a delta-A650 of 1 in 1 min at 25°C in the insulin reduction assay. Purity: >95% by SDS-PAGE. After reconstitution, store at -80°C and avoid freeze and thaw cycles.
Especificaciones

Especificaciones

P10599
Control
7295
7.5
E. coli
RUO
TXN
Unconjugated
E. coli
Lyophilized
purified
1mg/mL
0.02M HEPES with no preservative; pH 7.5
Human Thioredoxin 1
0.5mg
-20°C
Human Thioredoxin 1
Human
Hu
Recombinant
Recombinant
Sugerencias de productos

Sugerencias de productos

Videos
SDS
Documentos

Documentos

Certificados
Ofertas especiales

Ofertas especiales

in vitro research only.