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T Cell Receptor Gamma/Delta Hamster, anti-Mouse, Biotin, Clone: GL3, STEMCELL Technologies

Hamster Monoclonal Antibody

Marca:  Stemcell Technologies 60104BT

Detalles adicionales : Peso : 0.00110kg

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Código de producto. 17199021

  • 562.59€ / 500 microgramos
Fecha estimada de envío: 08-11-2022
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Descripción

Descripción

  • The GL3 antibody reacts with the δ chain of the murine T cell receptor γ/δ (TCRγ/δ or TCR gamma/delta), a subtype of the TCR involved in the recognition of both peptide and lipid antigens
  • TCRγ/δ comprises a heterodimer (∼ 80 kDa in humans) of disulfide-linked γ and δ subunits that associates with CD3 on the cell surface
  • It is a member of the immunoglobulin superfamily
  • TCRγ/δ is expressed on a subpopulation of T cells in the circulation but may be found on up to 50% of the T cells in epithelial cell-rich tissues
  • These cells have roles in oral and tumor-associated tolerance as well as autoimmune disease and have been described as a link between the adaptive and innate immune responses
  • Once activated, they secrete effector cytokines in a subtype- and context-specific manner
  • Most γ/δ T cells are CD4-/CD8-, though some express CD8
  • The GL3 antibody recognizes an epitope in the constant region of the δ chain and can reportedly activate TCRγ/δ+ cells
Especificaciones

Especificaciones

T Cell Receptor Gamma/Delta
Monoclonal
Biotin
500 μg
Mouse
T Cells, T Cells, Other Subsets
Blocking Assay, Functional Assay, Immunofluorescence, Flow Cytometry, Immunohistochemistry
GL3
Hamster
Primary
IgG2 κ
Videos
SDS
Documentos
Certificados
Ofertas especiales

Ofertas especiales