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Estaurosporina, + 99 %, Thermo Scientific Chemicals

Catalog Number p-7042530
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Cantidad:
1 mg
5 mg
10 mg
62996-74-1
C28H26N4O3
466.541
MFCD00077402
HKSZLNNOFSGOKW-ZYSRIHRCSA-N
Antibiotic AM-2282
49831000
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
62996-74-1
C28H26N4O3
466.541
MFCD00077402
HKSZLNNOFSGOKW-ZYSRIHRCSA-N
Antibiotic AM-2282
49831000
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC

Staurosporine (staurosporin, CAS # 62996-74-1) is a bacterial alkyloid isolated from Streptomyces staurosporeus.

Broad spectrum protein kinase inhibitor Staurosporine is used as anti-fungal and anti-hypertensive, which results to study the anti-cancer treatment. It acts as a precursor to protein kinase inhibitor midostaurin. It is also used to induce cell death in Swiss Webster primary macrophage cells and to study the effect of caspase activation on human sperm quality.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Aplicaciones
La estaurosporina, un inhibidor de amplio espectro de proteína quinasas, se utiliza como antifúngico y antihipertensor, y para el estudio del tratamiento contra el cáncer. Actúa como precursor del inhibidor de la proteína quinasa midostaurina. También se utiliza para inducir la muerte celular de macrófagos primarios de ratones Swiss Webster y para estudiar el efecto de la activación de la caspasa sobre la calidad del esperma humano.

Solubilidad
Soluble en DMSO o etanol. Soluble en dimetilsulfóxido, dimetilformamida, acetato de etilo, acetona caliente y etanol. Ligeramente soluble en cloroformo y metanol. Insoluble en agua.

Notas
Almacenar en un lugar fresco. Incompatible con agentes oxidantes fuertes.
TRUSTED_SUSTAINABILITY
Nombre del producto químico o material Staurosporine
Tipo Staurosporine
Forma física Polvo
Punto de fusión 240°C to 243°C
Beilstein 1060573
Índice Merck 14,8802
Información de solubilidad Soluble in DMSO or ethanol;Soluble in dimethyl sulfoxide ,dimethyl formamide,ethyl acetate,hot acetone and ethanol; Slightly soluble in chloroform and methanol; Insoluble in water.
Formula Weight (peso de la fórmula) 466.54
Porcentaje de pureza ≥99%
Color Amarillo
Cantidad 1 mg
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RUO – Research Use Only

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