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SMTN Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 23567-1-AP-150UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16812395

  • 399.00€ / 150 microlitros
Fecha estimada de envío: 17-04-2024
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Descripción

Descripción

Smoothelin is a constituent of the smooth muscle cell (SMC) cytoskeleton. Antibodies directed to smoothelin are a useful tool to monitor SMC differentiation. Smoothelin is exclusively expressed in fully differentiated (contractile) SMCs. RNA and protein analyses reveal a broad species distribution of this protein. Cells with SMC-like characteristics, such as myofibroblasts, myoepithelial cells, and skeletal and cardiac muscle do not contain smoothelin. Confocal scanning laser microscopy of tissue sections, as well as transfection studies, show a filamentous organization of smoothelin that is different from that of desmin and vimentin. Smoothelin colocalizes with actin stress fibers. Two tissue specific isoforms have been identified: a 59 kDa isoform specific for visceral SMC; and a 100 kDa specific for vascular SMC. Human smoothelin is encoded by a single copy gene which is located on chromosome 22.
Especificaciones

Especificaciones

SMTN
Polyclonal
Unconjugated
SMTN
smoothelin, SMSMO, SMTN
Rabbit
Antigen Affinity Chromatography
RUO
29856, 6525
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.33 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P53814, Q921U8
SMTN
SMTN Fusion Protein Ag19983
150 μL
Primary
Human, Mouse
Antibody
IgG
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