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SMAD4/DPC4 Ab-1, Mouse Monoclonal Antibody,Lab Vision™ Epredia™
Provide accurate, reproducible results with the Epredia™ SMAD4/DPC4 Ab-1, Mouse Monoclonal Antibody.
Marca: Epredia MS-865-B1
Detalles adicionales : Peso : 1.00000kg
Descripción
DPC4 (also named SMAD4; small mothers against decapentaplegic deleted in pancreatic carcinoma). The family of SMAD molecules comprises essential mediators of transforming growth factor β (TGF-β) signaling. To date, seven members of this family have been identified, each of which plays a specific and separate role in mediating TGF-β superfamily gene transcription. At least two different members, Smad2 and Smad4/DPC4, have been implicated in human cancer and appear to have tumor-suppressor functions whose inactivation may play an important role in the histogenesis of pancreatic and colorectal malignancy and possibly other human cancers as well.Host Species: Mouse
Clone: SMD46; same as DCS-46
Isotype: IgG1
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Purified recombinant DPC4 protein
Molecular Weight: 60kDa
Positive Control: Ls174T, HT29, Raji, Jurkat cells
Cellular Localization: Nuclear
Recommended for:
Western Blotting
Immunofluorescence
Immunoprecipitation (Native and denatured)
Note:
USA: RUO; Int'l: RUO
Especificaciones
SMAD4/DPC4 Ab-1 | |
Monoclonal | |
200μg/mL | |
Mouse | |
500 μL | |
Cancer and Tumor Biology | |
Human | |
IgG1 |
Immunofluorescence, Immunoprecipitation, Western Blot | |
SMD46; same as DCS-46 | |
Biotin | |
Purified recombinant DPC4 protein | |
RUO | |
Primary | |
Concentrated |