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SELPLG Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 23605-1-AP-150UL
Detalles adicionales : Peso : 0.00010kg
Descripción
This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.Especificaciones
SELPLG | |
Polyclonal | |
Unconjugated | |
SELPLG | |
CD162, CLA, PSGL 1, PSGL1, selectin P ligand, SELPLG | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
6404 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.37 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q14242 | |
SELPLG | |
SELPLG Fusion Protein Ag19394 | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgG |