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SCNN1G Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 13943-1-AP-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16812384

  • 109.00€ / 20 microlitros

Envío estimado: 29-10-2021

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Descripción

Descripción

Epithelial sodium channels are amiloride-sensitive members of the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels. Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region. There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein. ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance. ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure. ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel. Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddel′s syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1).
Especificaciones

Especificaciones

SCNN1G
0.25 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P37091, P51170, Q9WU39
ENaCg, ENaCgamma, Gamma ENaC, Gamma NaCH, PHA1, SCNEG, SCNN1G
Rabbit
IgG
20 μL
-20°C
Primary
20278, 24768, 6340
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
SCNN1G
Liquid
SCNN1G
SCNN1G Fusion Protein Ag5020
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Human, Rat
Videos
SDS
Documentos
Certificados