Learn More
Thermo Scientific Chemicals SB 225002
Descripción
SB 225002 is a selective non-peptide CXCR2 inhibitor which suppresses IL-8 induced neutrophil chemotaxis and margination. In addition, SB 225002 reduces MPO activity, IL-1β, MIP-2, and keratinocyte-derived chemokine (KC) levels. Further studies suggest that SB 225002 decreases the expression of vascular endothelial growth factor, inducible NOS (NO synthase), and Cox-2 (cyclooxygenase-2 proteins) in colon tissue.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Especificaciones
Cantidad | 5mg |
Descripción | Amarillo |
Contenido y almacenamiento | −30°− hasta 10 °C |
Para utilizar con (aplicación) | Un potente, selectivo y competitivo antagonista del receptor acoplado de proteína G CXCR2 |
Formula Weight (peso de la fórmula) | 352,10g/mol |
Sensibilidad | Sensible a la humedad |
Solubilidad | Soluble a 100 mm en DMSO y a 50 mm en etanol |
Tipo de producto | Reactivo de transducción de la señal |
Formulario | Sólido |
RUO – Research Use Only