missing translation for 'onlineSavingsMsg'
Learn More

Retinoblastoma (Rb) Ab-5, Mouse Monoclonal Antibody,Lab Vision™ Epredia™

Provide accurate, reproducible results with the Epredia™ Retinoblastoma (Rb) Ab-5, Mouse Monoclonal Antibody.

Marca:  Epredia MS-595-P

Detalles adicionales : Peso : 1.00000kg

 Ver más versiones de este producto

Código de producto. 12681697

  • 444.00€ / 1 ml

Envío estimado: 29-06-2021

Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.


Descripción

Descripción

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Host Species: Mouse

Clone: XZ133

Isotype: IgG1

Species Reactivity: Human, Mouse (strong) and Chicken (strong). Does not react with Xenopus. Others not known.

Epitope: aa 620-665

Immunogen: Recombinant human Rb protein corresponding to amino acids 387-928

Molecular Weight: 105kDa

Positive Control: Ls174T, HT29, HUVEC cells

Cellular Localization: Nuclear Ab-5 reacts with the hyperphosphorylated as well as the under phosphorylated form of the Rb protein.

Recommended for:

  • Immunohistochemistry (Not suitable)
  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Especificaciones

Especificaciones

Retinoblastoma (Rb) Ab-5
Monoclonal
200μg/mL
Concentrated
Recombinant human Rb protein corresponding to amino acids 387-928
1mL
Cancer and Tumor Biology
Primary
Chicken, Human, Murine
Immunofluorescence, Immunoprecipitation
XZ133
Unconjugated
Murine
IgG1
RUO
Primary
Monoclonal
Videos
SDS
Documentos
Certificados