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enQuireBio™ Recombinant Chicken GH Antagonist Protein

A cDNA sequence encoding the GH Antagonist was constructed and used to recombinantly synthesize the protein.

Marca:  enQuireBio™ QP10641-1mg

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15924498

  • 968.00€ / 1 miligramo


Fecha de envío estimada
del proveedor 10-04-2019
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Especificación

Especificación

GH Antagonist Protein
1 mg
< 1.0 EU per ug protein as determined by the LAL method.
Recombinant Protein
E. coli
The protein was lyophilized from a concentrated (1 mg/ml) solution with 0.3% NaHCO3 pH 8.
Greater than 98.0% as determined by:(a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Research Use Only
Recombinant Chicken Growth Hormone G119R mutant did not bind to ovine GHR-ECD and was devoid of any biological activity in FDC-P1 3B9 cells. However, in binding experiments that were carried out using chicken liver membranes, both ovine GH and chicken GH showed similar IC50 values in competition with 125I-ovine GH, while the IC50 of G119R mutein was 10-fold higher. These results emphasize the importance of species specificity and indicate the possibility of antagonistic activity of chGH G119R in homologous system.
Chicken
Untagged
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