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enQuireBio™ Recombinant Chicken GH Antagonist Protein

A cDNA sequence encoding the GH Antagonist was constructed and used to recombinantly synthesize the protein.

137.00€ - 1285.00€

Especificaciones

Nombre GH Antagonist Protein
Estado normativo Research Use Only
Concentración de endotoxinas < 1.0 EU per ug protein as determined by the LAL method.
Actividad biológica Recombinant Chicken Growth Hormone G119R mutant did not bind to ovine GHR-ECD and was devoid of any biological activity in FDC-P1 3B9 cells. However, in binding experiments that were carried out using chicken liver membranes, both ovine GH and chicken GH showed similar IC50 values in competition with 125I-ovine GH, while the IC50 of G119R mutein was 10-fold higher. These results emphasize the importance of species specificity and indicate the possibility of antagonistic activity of chGH G119R in homologous system.
Tipo de producto Recombinant Protein
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Productos 3
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
15934498
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enQuireBio™
QP10641-20UG
20 μg
137.00€
20 microgramos
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Fecha estimada de envío: 14-06-2024
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15914498
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enQuireBio™
QP10641-100UG
100 μg
212.00€
100 microgramos
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Fecha estimada de envío: 14-06-2024
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Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
15924498
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enQuireBio™
QP10641-1MG
1 mg
1285.00€
1 miligramo
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»
Fecha estimada de envío: 14-06-2024
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Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

Especificaciones

Especificaciones

GH Antagonist Protein
< 1.0 EU per ug protein as determined by the LAL method.
Recombinant Protein
E. coli
The protein was lyophilized from a concentrated (1 mg/ml) solution with 0.3% NaHCO3 pH 8.
Research Use Only
Recombinant Chicken Growth Hormone G119R mutant did not bind to ovine GHR-ECD and was devoid of any biological activity in FDC-P1 3B9 cells. However, in binding experiments that were carried out using chicken liver membranes, both ovine GH and chicken GH showed similar IC50 values in competition with 125I-ovine GH, while the IC50 of G119R mutein was 10-fold higher. These results emphasize the importance of species specificity and indicate the possibility of antagonistic activity of chGH G119R in homologous system.
Chicken
Untagged
Greater than 98.0% as determined by:(a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
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Documentos

Documentos

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