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RBM25 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 25297-1-AP-150UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16813885

  • 399.00€ / 150 microlitros
Fecha estimada de envío: 17-04-2024
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Descripción

Descripción

RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5′-splice site (5′-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5′-ss usage through the 5′-CGGGCA-3′ RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5′ ss in a 5′-CGGGCA-3′-dependent manner. Binds to the exonic splicing enhancer 5′-CGGGCA-3′ RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.
Especificaciones

Especificaciones

RBM25
Polyclonal
Unconjugated
RBM25
fSAP94, NET52, Protein S164, RBM25, RED120, RNA binding motif protein 25, RNA binding protein 25, RNPC7, S164
Rabbit
Antigen Affinity Chromatography
RUO
58517, 67039
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.25 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
B2RY56, P49756
RBM25
RBM25 Fusion Protein Ag18244
150 μL
Primary
Human, Mouse
Antibody
IgG
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Ofertas especiales

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