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ACROBiosystems Rat TIGIT Protein, Fc Tag
423.38€ - 2661.24€
Especificaciones
| Peso molecular | 39.9 kDa |
|---|---|
| Fuente | Rat TIGIT, Fc Tag (TIT-R5258) is expressed from human 293 cells (HEK293). It contains AA Ala 17 - Ala 138 (Accession # D3ZTQ2). |
| Inmunógeno | Ala 17 - Ala 138 |
| Requisitos de almacenamiento | -20°C |
| Alias de gen | TIGIT,VSIG9,VSTM3 |
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|---|---|---|---|---|---|---|---|---|---|
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|
15897787
|
ACROBiosystems
TIT-R5258-50UG |
50 μg |
423.38€
50 microgramos |
Fecha estimada de envío: 30-04-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
|
15887787
|
ACROBiosystems
TIT-R5258-1MG |
1 mg |
2661.24€
1 miligramo |
Fecha estimada de envío: 30-04-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is also known as V-set and immunoglobulin domain-containing protein 9 (VSIG9), V-set and transmembrane domain-containing protein 3 (VSTM3),which belongs to single-pass type I membrane protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level). TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 39.9 kDa. As a result of glycosylation, the protein migrates as 48-55 kDa under reducing (R) condition, and 85-110 kDa under non-reducing (NR) condition (SDS-PAEspecificaciones
| 39.9 kDa | |
| Ala 17 - Ala 138 | |
| TIGIT,VSIG9,VSTM3 | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| Rat TIGIT, Fc Tag (TIT-R5258) is expressed from human 293 cells (HEK293). It contains AA Ala 17 - Ala 138 (Accession # D3ZTQ2). | |
| -20°C | |
| TIGIT | |
| Rat | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Immune Checkpoint Proteins |