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PRKAR2A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 10142-2-AP-150UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16816333

  • 319.00€ / 150 microlitros

Envío estimado: 21-10-2021

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Descripción

Descripción

This antibody got two bands about 45 kDa and 50-55 kDa in western blotting, and the 50-55 kDa may be caused by phosphorylation.

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of AMPK.
Especificaciones

Especificaciones

PRKAR2A
0.31 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P12367, P12368, P13861
PKR2, PRKAR2, PRKAR2A
Rabbit
IgG
150 μL
-20°C
Primary
19087, 29699, 5576
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
PRKAR2A
Liquid
Prkar2a
PRKAR2A Fusion Protein Ag0203
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Videos
SDS
Documentos
Certificados