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Phospho-RPS6KA1 (Ser380) Rabbit anti-Human, Unconjugated, Clone: 7F23, Proteintech
Rabbit Monoclonal Antibody
Marca: Proteintech 80108-1-RR-20UL
Detalles adicionales : Peso : 0.00010kg
Descripción
The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed serine/threonine kinases and play an important role in the MAPK signaling cascade and act downstream of ERK1/2 signaling. It can mediate mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77. RSK1 (RPS6KA1) is also designated as p90RSK associated with cellular proliferation, survival and differentiation. It has been reported that the phosphorylation of RPS6KA1 at Ser380 is involved in autophosphorylation by activation of the C-terminal kinase domain. (PMID: 16458888, 30813401, 17259979, 10679322)
Especificaciones
| Phospho-RPS6KA1 (Ser380) | |
| Monoclonal | |
| 500 μg/mL | |
| Rabbit | |
| Primary | |
| Human, Mouse, Rat | |
| IgG |
| Western Blot, ELISA | |
| 7F23 | |
| Unconjugated | |
| 20 μL | |
| 6195 | |
| Liquid |