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Invitrogen™ Phospho-PLK1 (Thr210) Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ 480028
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Descripción
Phospho-PLK1 (Thr210) Polyclonal Antibody for Western Blot
PLK1 is a serine/threonine kinase that is thought to function in cell mitosis and regarded as a marker of cell proliferation. It has been found to play a critical role in carcinogenesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, CCNB1, CDC25C, CEP55, ECT2, ERCC6L, FBXO5/EMI1, FOXM1, KIF20A/MKLP2, CENPU, NEDD1, NINL, NPM1, NUDC, PKMYT1/MYT1, KIZ, PPP1R12A/MYPT1, PRC1, RACGAP1/CYK4, SGOL1, STAG2/SA2, TEX14, TOPORS, p73/TP73, TPT1 and WEE1. Plays a key role in centrosome functions and the assembly of bipolar spindles by phosphorylating KIZ, NEDD1 and NINL.
Especificaciones
| Phospho-PLK1 (Thr210) | |
| Polyclonal | |
| Unconjugated | |
| Plk1 | |
| cell cycle regulated protein kinase; Plk; PLK 1; Plk1; PLK-1; plk1.S; plx1; polo (Drosophia)-like kinase; polo like kinase; polo like kinase 1; polo like kinase 1 S homeolog; polo-like kinase; polo-like kinase 1; polo-like kinase homolog; polo-like protein kinase; serine/threonine-protein kinase 13; Serine/threonine-protein kinase PLK1; STPK13; STPK14; Unknown (protein for MGC:133927); XELAEV_18047692mg | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 25515, 5347 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.25 mg/mL | |
| 10mM HEPES buffered saline with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5 | |
| P53350, Q62673 | |
| Plk1 | |
| Immunogen is surrounding Tyr210 of PLK1. | |
| 100 μL | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG |
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