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Phospho-CD247 (CD3 zeta) (Tyr142) Mouse anti-Human,Mouse, APC, Clone: 3ZBR4S, eBioscience™

Mouse Monoclonal Antibody

Marca:  Affymetrix eBioscience 17-2478-41

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15923214

  • 118.00€ / 25 tests


Fecha de envío estimada
del proveedor 27-03-2019
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Descripción

Descripción

A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases.
Especificación

Especificación

Phospho-CD247 (CD3 zeta) (Tyr142)
Monoclonal
5 μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
24161, P20963
CD3z
Mouse
IgG2b, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
12503, 919
Flow Cytometry
3ZBR4S
APC
CD247
Liquid
CD247
Human CD247 peptide phosphorylated on Tyr142
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Mouse
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