missing translation for 'onlineSavingsMsg'
Learn More
Learn More
PAK4/6/7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00€ - 399.00€
Especificaciones
Antígeno | PAK4/6/7 |
---|---|
Concentración | 0.2 mg/mL |
Aplicaciones | Immunohistochemistry (Paraffin), Immunoprecipitation |
Clasificación | Polyclonal |
Conjugado | Unconjugated |
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
---|---|---|---|---|---|---|---|---|---|
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
16830184
|
Proteintech
12460-1-AP-20UL |
20 μL |
140.00€
20 microlitros |
Fecha estimada de envío: 08-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
16820184
|
Proteintech
12460-1-AP-150UL |
150 μL |
399.00€
150 microlitros |
Fecha estimada de envío: 08-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
The antibody can recognize PAK4/6/7. PAK4/6/7 belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily.
PAK4 is highly expressed in prostate, testis and colon. PAK4 interacts tightly with GTP-bound but not GDP-bound CDC42 and weakly with RAC. PAK4 phosphorylates and autophosphorylates and also activates the JNK pathway. PAK5, a member of the PAK family of protein kinases contains a CDC42/Rac1 interactive binding (CRIB) motif at the N-terminus and a Ste20-like kinase domain at the C-terminus. PAK5 preferentially binds to CDC42 in the presence of GTP and the CRIB motif is essential for this interaction. PAK6 protein cotranslocates into the nucleus with androgen receptor, which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development, in response to androgen. PAK6 was initially identified as an androgen receptor in a yeast two hybrid screen and was found to be highly expressed in testis and prostate tissues. Later experiments have shown it to be activated by MAP kinase 6 and p38 MAP kinase, suggesting that PAK6 may play a role in the cellular response to stress-related signals.Especificaciones
PAK4/6/7 | |
Immunohistochemistry (Paraffin), Immunoprecipitation | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
O96013, Q3ULB5, Q8BTW9, Q8C015, Q9NQU5, Q9P286 | |
10298, 214230, 241656, 292756, 296078, 311450, 56924, 57144, 70584 | |
PAK4/6/7 Fusion Protein Ag3127 | |
Primary | |
-20°C | |
PAK4 |
0.2 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
KIAA1264, p21 activated kinase 5, p21 activated kinase 7, PAK 5, PAK 7, PAK5, PAK7 | |
Pak4, PAK5, PAK6, Pak7 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |