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OXER1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 55202-1-AP-150UL
Detalles adicionales : Peso : 0.00010kg
Descripción
This antibody is specific to OXER1.
TG1019 is a G protein-coupled receptor that functions as a chemoattractant for eosinophils and neutrophils. TG1019 is expressed in various tissues except the brain, with the highest expression in liver, kidney, peripheral leukocyte, lung and spleen. TG1019 interacts with the protein OXE to form TG1019/OXE, a Galpha i/o protein-coupled receptor. Signals from TG1019 are transduced via a Galpha i/o protein to PLC/calcium, MEK/ERK and PI3K/Akt pathways. Signal transduction from TG1019 following stimulation with 5-oxo-6E,8Z,11Z,14Z eicosatetraenoic acid (5-oxo-ETE) induces intracellular calcium mobilization and rapid activation of MEK/ERK and PI3K/Akt pathways. TG1019 also may play a role in downregulating cAMP production.Especificaciones
| OXER1 | |
| Polyclonal | |
| Unconjugated | |
| OXER1 | |
| G protein coupled receptor 170, GPCR, GPR170, OXER1, oxoeicosanoid (OXE) receptor 1, Oxoeicosanoid receptor 1, TG1019 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 165140 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot | |
| 0.25 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q8TDS5 | |
| OXER1 | |
| Peptide | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |