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Invitrogen™ Human NUAK2, GST Tag Recombinant Protein

NUAK2 or SNF1/AMP kinase-related kinase (SNARK) is a member of the NUAK family of SNF1-like kinase 2. Recombinant full-length human NUAK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Marca:  Invitrogen™ PV6376

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15499003

  • 493.00€ / 10 microgramos
Fecha estimada de envío: 23-04-2024
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Descripción

Descripción

NUAK2 is activated by muscle contraction and is a unique mediator of contraction-stimulated glucose transport in skeletal muscle (1). NUAK2 is involved in cellular stress responses linked to obesity and type 2 diabetes. NUAK2 shows kinase activity against a synthetic test peptide and the activity in keratinocytes is increased by AMP and 5-amino-4-imidazolecarboxamide riboside, implying that AMPK kinase-dependent pathway can activate NAUK2. Glucose deprivation also increases NAUK2 activity in baby hamster kidney fibroblasts.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Especificaciones

Especificaciones

Kinase Assay
10μg
Human
GST Tag
Biochemical binding/kinetic
NUAK2
Kinases & Inhibitors
96.3 kDa
SNARK, FLJ90349, DKFZP434J037, DKFZp686F01113
Recombinant
Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
Serine/Threonine Kinase
Baculovirus
Recombinant, Full Length
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