missing translation for 'onlineSavingsMsg'
Learn More

NR2F6 Mouse anti-Human, Clone: 2H2B8, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 60117-2-IG-150UL

Detalles adicionales : Peso : 0.00010kg

 Ver más versiones de este producto

Código de producto. 16817085

  • 319.00€ / 150 microlitros

Envío estimado: 21-10-2021

Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.


Descripción

Descripción

Transcription factor predomitly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5′-AGGTCA-3′ direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and may be involved in induction and/or maintece of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock; is required early in the development of the locus coeruleus (LC).
Especificaciones

Especificaciones

NR2F6
2H2B8
Unconjugated
NR2F6
Liquid
NR2F6
NR2F6 Fusion Protein Ag7614
Protein G
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P10588
EAR 2, EAR2, ERBAL2, NR2F6, V erbA related protein 2
Mouse
IgG1
150 μL
-20°C
Primary
2063
Videos
SDS
Documentos
Certificados