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Myocilin Mouse anti-Human, Mouse, Porcine, Rat, Clone: 4B1F6, Proteintech
Mouse Monoclonal Antibody
140.00€ - 399.00€
Especificaciones
Antígeno | Myocilin |
---|---|
Clon | 4B1F6 |
Concentración | 1 mg/mL |
Aplicaciones | Immunohistochemistry (Paraffin), Western Blot |
Clasificación | Monoclonal |
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
---|---|---|---|---|---|---|---|---|---|
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
16827485
|
Proteintech
60357-1-IG-20UL |
20 μL |
140.00€
20 microlitros |
Fecha estimada de envío: 07-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
16817485
|
Proteintech
60357-1-IG-150UL |
150 μL |
399.00€
150 microlitros |
Fecha estimada de envío: 07-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
Myocilin is an extracellular protein expressed in the eye, including the retina, trabecular meshwork and ciliary body. Myocilin can form homomultimers in vivo and can also associate with components of the ECM via interactions with the Hep II domain of FibroPVRL1. In addition, myocilin interacts with myosin regulatory light chain, a component of the myosin motor protein complex. This interaction implies a role for myocilin in the actomyosin system, linking myocilin to the functional status of the trabecular meshwork (TM), which is responsible for controlling the intraocular pressure (IOP). Alterations in functions of the TM may lead to IOP elevation and development of glaucoma, a major cause of blindness. Myocilin is encoded by MYOC (also designated TIGR), a gene that maps to the GLC1A locus on chromosome 1q24.3 and is susceptible to mutations. Mutations in the MYOC gene are specifically linked with primary open angle glaucoma (POAG), a blinding disease characterized by progressive loss of retinal ganglion cells.Especificaciones
Myocilin | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
GLC1A, GPOA, JOAG, JOAG1, MYOC, myocilin, TIGR | |
Myoc | |
IgG2a | |
Protein A | |
Antibody |
4B1F6 | |
Immunohistochemistry (Paraffin), Western Blot | |
Unconjugated | |
Mouse | |
Human, Mouse, Porcine, Rat | |
O70624, Q99972, Q9R1J4 | |
17926, 397046, 4653, 81523 | |
Myocilin Fusion Protein Ag5492 | |
Primary | |
-20°C | |
MYOC |