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MTM1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Marca:  Thermo Scientific PA552725

Detalles adicionales : Peso : 0.02000kg

Código de producto. 15790671

  • 415.00€ / 100 microlitros


Fecha de envío estimada
del proveedor 29-10-2019
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Descripción

Descripción

Human MTM1, a 603 amino-acid protein, is mutated in myotubular myopathy. The largely related protein hMTMR2 is found mutated in a recessive form of Charcot-Marie-tooth neuropathy. Myotubularin is primarily a lipid phosphatase that acts on hosphatidylinositol 3-monophosphate and is involved in the regulation of the phosphatidylinositol 3-kinase (PI 3-kinase) pathway and membrane trafficking. Wildtype myotubularin can directly dephosphorylate PI 3-P and PI 4-P in vitro. Thus, it decreases PI 3-P levels by down-regulating PI 3-K activity and by facilitating the degradation of PI 3-P.
Especificaciones

Especificaciones

MTM1
Polyclonal
Unconjugated
MTM1
Liquid
MTM1
Recombit protein corresponding to Human MTM1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry, Western Blot
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q13496
MTM1; myotubular myopathy 1; CNM; MTMX; XLMTM; myotubularin; myotubularin 1
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
4534
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