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STEMCELL Technologies Mouse Recombinant IL-7
Interleukin 7
Marca: STEMCELL Technologies 78054.1
Detalles adicionales : Peso : 0.00110kg
Descripción
- Interleukin 7 (IL-7) is a member of the type I cytokine family that is critical for T and B cell development and survival
- It is produced by non-hematopoietic cells in the thymus, lymphoid organs, and by bone marrow stromal cells (Lundström et al.) IL-7 binds to a receptor composed of common gamma chain and IL-7Ra (CD127) and signals through the JAK/STAT and PI3K pathways
- IL-7 regulates the survival of naïve and memory CD4+ and CD8+ T cells, γδ T cells, NK T cells, innate lymphoid cells, and T regulatory cells (Carrette & Surh), and provides signals to promote survival, proliferation, and differentiation during B cell development (Clark et al.; Corfe & Paige)
Especificaciones
| Interleukin-7, LP-1, Lymphopoietin 1, Pre-B cell factor | |
| 10 μg | |
| Hematopoietic Stem and Progenitor Cells; Lymphocytes | |
| ≥95% |