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ACROBiosystems Mouse IgG2a Fc Protein, Tag Free

Marca:  ACROBiosystems IGA-M5207-200UG

Detalles adicionales : Peso : 0.00001kg

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Código de producto. 15877007

  • 335.90€ / 200 microgramos
Fecha estimada de envío: 07-02-2023
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Descripción

Descripción

Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis.

This protein carries no "e;tag"e;. The protein has a calculated MW of 26.4 kDa. As a result of glycosylation, the protein migrates as 30-35 kDa under reducing (R) condition, and 55-60 kDa under non-reducing (NR) condition (SDS-PAGE).
Especificaciones

Especificaciones

CAC20702
26.4 kDa
200 µg
Glu 98 - Lys 330
IgG2A
Unconjugated
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
HEK293
Mouse
Powder
>90% as determined by SDS-PAGE
Mouse IgG2a Fc, Tag Free (IGA-M5207) is expressed from human 293 cells (HEK293). It contains AA Glu 98 - Lys 330 (Accession # CAC20702).
-20°C
IgG2a Fc
Tag Free
Less than 1.0 EU / µg by the LAL method.
Other Recombinant Proteins
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