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MLL5 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

140.00€ - 399.00€

Especificaciones

Antígeno MLL5
Concentración 0.27 mg/mL
Aplicaciones Immunocytochemistry, Immunofluorescence, Western Blot
Clasificación Polyclonal
Conjugado Unconjugated
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
16813234
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Proteintech
14540-1-AP-20UL
20 μL
140.00€
20 microlitros
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Fecha estimada de envío: 17-04-2024
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16803234
Ver documentos Detalles de la promoción
Proteintech
14540-1-AP-150UL
150 μL
399.00€
150 microlitros
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Ahorre hasta 
»
Fecha estimada de envío: 17-04-2024
para ver el stock
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

The mixed lineage leukemia (MLL) gene family comprise a group of Histone H3 lysine 4 (H3K4) methyltransferases within the larger SET1 family. The founding member MLL commonly undergoes translocations in infantile leukemia and displays increased expression in some adult myeloid leukemias. MLL2, also designated ALR, exists within a complex of proteins. MLL2 is important for mouse embryonic development and may be involved in adhesion-related cytoskeletal events affecting cell growth and survival. The MLL2 gene maps to the human locus 19q13.1, which is a frequent target of rearrangement or amplification in solid tumors. MLL3 or its paralogue MLL4 associate with activating signal cointegrator-2 (ASC-2), which regulates ligand-dependent H3K4 trimethylation and expression of LXR-target genes. MLL3 maps to a location on human chromosome 7 that is often deleted in myeloid disorders. MLL3 also exhibits higher expression in peripheral blood, placenta, pancreas, testis, and fetal thymus. MLL5 localizes to the nucleus and forms intranuclear protein complexes, which may regulate chromatin remodeling and cellular growth suppression. The gene encoding human MLL5 lies within chromosome band 7q22.3, a region deleted in cytogenetic aberrations of acute myeloid maligcies.
Especificaciones

Especificaciones

MLL5
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
Rabbit
Human, Mouse
Q3UG20, Q8IZD2
55904, 69188
MLL5 Fusion Protein Ag6044
Primary
-20°C
KMT2E
0.27 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
HDCMC04P, KMT2E, Lysine N methyltransferase 2E, MLL5
KMT2E
IgG
Antigen Affinity Chromatography
Antibody
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SDS
Documentos

Documentos

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