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Thermo Scientific Chemicals Antagonista de MIF, ISO-1
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Cantidad:
5mg
25mg
Descripción
MIF Antagonist, ISO-1 inhibits MIF dopachrome tautomerase activity by binding to its catalytic active site (IC50 = 7 μM for D-dopachrome tautomerase) and suppresses the production of TNFα, PGE2 and COX-2 in human monocytes and arachidonic acid in RAW 264.7 macrophages. MIF Antagonist, ISO-1 has been shown to exhibit antidiabetogenic properties in immunoinflammatory diabetic mouse model.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Especificaciones
| Cantidad | 5mg |
| Descripción | Amarillo pálido |
| Contenido y almacenamiento | −30°− hasta 10 °C |
| Para utilizar con (aplicación) | Un compuesto de isoxazolina que puede penetrar en las células. |
| Formula Weight (peso de la fórmula) | 235,24g/mol |
| Sensibilidad | Sensible a la luz |
| Tipo de producto | Reactivo de transducción de la señal |
| Formulario | Sólido |
| Clave InChI | CLVQGFPQFNASJH-UHFFFAOYNA-N |
| SMILES | COC(=O)CC1CC(NO1)=C1C=CC(=O)C=C1 |
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RUO – Research Use Only
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