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Mast Cell Chymase Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 18189-1-AP-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16818254

  • 140.00€ / 20 microlitros
Fecha estimada de envío: 17-04-2024
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Descripción

Descripción

This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases.
Especificaciones

Especificaciones

Mast Cell Chymase
Polyclonal
Unconjugated
CMA1
Alpha chymase, chymase, chymase 1, mast cell, CMA1, CYH, CYM, Mast Cell Chymase, Mast cell protease I, Mcpt 5, Mcpt5, MCT1
Rabbit
Antigen Affinity Chromatography
RUO
1215, 17228, 25627
-20°C
Liquid
Immunoprecipitation, Western Blot
0.25 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P21844, P23946, P50339
Cma1
Mast Cell Chymase Fusion Protein Ag12909
20 μL
Primary
Mouse, Rat, Human
Antibody
IgG
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