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Invitrogen™ Human MAP2K4 (MEK4), GST Tag Recombinant Protein

Human MAP2K4 (MEK4), GST Tag Recombinant Protein

Marca:  Invitrogen™ A33379

Detalles adicionales : Peso : 0.00900kg

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Código de producto. 17138795

  • 7580.00€ / 1 miligramo
Fecha estimada de envío: 30-04-2024
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Descripción

Descripción

MAP2K4 (MEK4) serine/threonine kinase (mitogen-activated protein kinase kinase 4) MEK4 or MKK4 is a dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and -2 as well as p38. MAP2K4 preferentially phosphorylates the tyrosine residue of JNKs. MAP2K4 mediates a variety of physiological and pathophysiological processes such as responses to cellular stresses and inflammatory cytokines. MAP2K4 is important for carcinogenesis; a loss-off-function mutation in MAP2K4 was found in lung and pancreatic tumors. Conversely, a pro-oncogenic role was also found for MAP2K4.
  • Validated for use with the LanthaScreen™ Eu Kinase Binding assay
  • Available in multiple pack sizes for convenient use
Especificaciones

Especificaciones

NP_003001
70.6 kDa
MAP Kinases
Human
GST Tag
Dry Ice
Full Length, Recombinant, Active
Kinase Assay
1 mg
Full Length
Recombinant
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Insect
Liquid
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