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![LRRK2 [R1441C] Human Protein 10μg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-650.jpg)
LRRK2 [R1441C] Human Protein
LRRK2 [R1441C] Human Protein
Marca: Invitrogen PV5858
Detalles adicionales : Peso : 0.00010kg
Descripción
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease, including the R1441C mutation in the GTPase domain.Related Links:
Especificaciones
| NP_940980.2 | |
| Pharma and Biopharma, Protein Assays and Analysis, Target and Lead Identification and Validation, Kinase Assay | |
| 205kDa | |
| 10μg | |
| For research use only. Not for use in diagnostic procedures | |
| LRRK2 R1441C | |
| LRRK2 R1441C was pre-diluted in enzyme dilution buffer and assayed in 20mM Tris (pH 7.5), 10mM MgCl2, 1mM EGTA, 1mM Na3VO4, 5mM β- glycerophosphate, 2mM DTT, 0.02% Polysorbate 20, 100μM ATP, 250μM ERM (LRRKtide) peptide substrate (RLGRDKYKTLRQIRQ) (PV5093) and trace [32P]-γ-ATP for 10 minutes at 30°C | |
| aa 970 to 2527 | |
| 46nmoles of phosphate transferred to ERM (LRRKtide) peptide substrate (RLGRDKYKTLRQIRQ) (PV5093) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 2.08μg/mL | |
| GST Tag | |
| Kinases and inhibitors | |
| Serine/threonine kinase |
| 0.28mg/mL | |
| Frozen | |
| LRRK2 [R1441C] Human Protein | |
| –80°C | |
| 1 Each | |
| LRRK2 [R1441C] Human Protein | |
| LRRK Kinase family | |
| LRRK2 [R1441C] Human Protein | |
| Human | |
| Baculovirus | |
| Frozen | |
| 90% by SDS-PAGE |
For Research Use Only. Not for use in diagnostic procedures.