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LIG4 Mouse anti-Human, Clone: 1H6C11, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 66705-1-IG-150UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16818835

  • 319.00€ / 150 microlitros

Envío estimado: 20-10-2021

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Descripción

Descripción

The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed.
Especificaciones

Especificaciones

LIG4
1H6C11
Unconjugated
LIG4
Liquid
LIG4
LIG4 Fusion Protein Ag3385
Protein G
RUO
Antibody
Monoclonal
Human
Immunofluorescence, Western Blot
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P49917
DNA ligase 4, DNA ligase IV, LIG4, ligase IV, DNA, ATP dependent
Mouse
IgG2a
150 μL
-20°C
Primary
3981
Videos
SDS
Documentos
Certificados