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LAMR1/RPSA Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 14533-1-AP-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16813224

  • 109.00€ / 20 microlitros

Envío estimado: 02-11-2021

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Descripción

Descripción

This antibody is a rabbit polyclonal antibody raised against full length RPSA of human origin. This antibody is specific to RPSA (LAMR1).67LR derived from homo- or hetero- dimerization of a 37 kDa cytosolic precursor (37LRP)], most probably by fatty acid

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Especificaciones

Especificaciones

LAMR1/RPSA
0.2 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P08865, P14206, P38983
37/67 kDa laminin receptor, 37LRP, 40S ribosomal protein SA, 67 kDa laminin receptor, 67LR, LAMBR, Laminin receptor, Laminin receptor 1, LamR, LAMR1, LBP/p40, LRP, LRP/LR, NEM/1CHD4, p40, ribosomal protein SA, RPSA
Rabbit
IgG
20 μL
-20°C
Primary
16785, 29236, 3921
Western Blot, Immunocytochemistry, Immunofluorescence
Unconjugated
RPSA
Liquid
Rpsa
LAMR1,RPSA Fusion Protein Ag6033
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Rat, Human, Mouse
Videos
SDS
Documentos
Certificados