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Epredia™ Lab Vision™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-1 Mouse Monoclonal Antibody, 200µg/mL, biotinylated, BSA and azide

Provide accurate, reproducible results with the Epredia™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-1, Mouse Monoclonal Antibody.

Marca:  Epredia™ MS-434-B1

Detalles adicionales : Peso : 1.00000kg

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Código de producto. 12691407

  • 505.00€ / 500 microlitros

Envío estimado: 02-07-2021

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Descripción

Descripción

X-Ray Repair Cross Complementing (XRCC1) plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase β through the N-terminal half. In testis XRCC1 is expressed at high levels. Cells with a mutation of this gene exhibit decreased single strand break repair and reduced recombination repair. They show increased double strand breaks, and sister chromatid exchange is increased up to 10-fold. The XRCC1 might serve as a scaffold protein during base excision-repair.

Host Species: Mouse

Clone: 33-2-5

Isotype: IgG2b

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Recombinant human XRCC1 protein

Molecular Weight: 85kDa

Positive Control: Ls174T, HT29 or HeLa cells; normal testis

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO

Especificaciones

Especificaciones

XRCC1 (X-Ray Repair Cross Complementing Protein1) Ab-1
Monoclonal
200μg/mL
Biotinylated Ab with BSA and Azide
Murine
IgG2b
RUO
Primary
Monoclonal
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
33-2-5
Biotin
Concentrated
Recombinant human XRCC1 protein
500μL
DNA Repair
Primary
Human, Rat
Videos
SDS
Documentos
Certificados