Epredia™ Lab Vision™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-1 Mouse Monoclonal Antibody, 200µg/mL, biotinylated, BSA and azide
Provide accurate, reproducible results with the Epredia™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-1, Mouse Monoclonal Antibody.
Marca: Epredia™ MS-434-B1
Detalles adicionales : Peso : 1.00000kg
DescripciónX-Ray Repair Cross Complementing (XRCC1) plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase β through the N-terminal half. In testis XRCC1 is expressed at high levels. Cells with a mutation of this gene exhibit decreased single strand break repair and reduced recombination repair. They show increased double strand breaks, and sister chromatid exchange is increased up to 10-fold. The XRCC1 might serve as a scaffold protein during base excision-repair.
Host Species: Mouse
Species Reactivity: Human and Rat. Others not known.
Epitope: Not determined
Immunogen: Recombinant human XRCC1 protein
Molecular Weight: 85kDa
Positive Control: Ls174T, HT29 or HeLa cells; normal testis
Cellular Localization: Nuclear
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native verified)
USA: RUO; Int'l: RUO
|XRCC1 (X-Ray Repair Cross Complementing Protein1) Ab-1|
|Biotinylated Ab with BSA and Azide|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|Recombinant human XRCC1 protein|