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Epredia™ Lab Vision™ XPA Ab-1 Mouse Monoclonal Antibody, 200µg/mL, BSA and azide

Provide accurate, reproducible results with the Epredia™ XPA Ab-1, Mouse Monoclonal Antibody.

Marca:  Epredia™ MS-650-R7

Detalles adicionales : Peso : 1.00000kg

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Código de producto. 12691917

  • 376.00€ / 7 ml

Envío estimado: 02-07-2021

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Descripción

Descripción

The XPA (xeroderma pigmentosum group A) protein specifically recognizes the UV-or chemically damaged DNA lesions, and triggers the nucleotide excision repair process. XPA binds to the replication protein A (RPA) or the excision repair cross complementing 1 protein (ERCC1). In the absence of nucleotide excision repair persisting (unrepaired) DNA lesions (adducts) may lead to the accumulation of gene mutations and ultimately to cancer. Xeroderma pigmentosum patients have a > 2000 fold increased risk to develop skin cancer at sun-exposed areas.

Host Species: Mouse

Clone: 12F5

Isotype: IgG2a/k

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human XPA protein

Molecular Weight: ∽40kDa

Positive Control: Ls174T or MCF-7 cells or human tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Especificaciones

Especificaciones

XPA Ab-1
Monoclonal
Unconjugated
Prediluted
Recombinant human XPA protein
7mL
DNA Repair
Primary
Human
Western Blot
12F5
Ready-to-use for IHC (UVLP)
Murine
IgG2a kappa
RUO
Primary
Monoclonal
Videos
SDS
Documentos
Certificados