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Epredia™ Lab Vision™ sm (Smith Antigen) Ab-1 Mouse Monoclonal Antibody, 200µg/mL, biotinylated, BSA and azide

Epredia™ sm (Smith Antigen) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

Marca:  Epredia™ MS-450-P1

Detalles adicionales : Peso : 1.00000kg

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Código de producto. 12691457

Cantidad Precio
1 483.00€ / 500 microlitros
6 456.73€ / 500 microlitros
Envío estimado: 29-06-2021

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Descripción

Descripción

The sm (Smith) is an autoantigen on a series of particles composed of RNA and protein. Unlike RNP, the sm antigen is resistant to RNase, but partially sensitive to trypsin. It is involved in the pathogenesis of Systemic lupus erythematosus (SLE). Antibodies to sm are found in 20-30% of patients with SLE.

Host Species: Mouse

Clone: Y12

Isotype: IgG3/κ

Species Reactivity: Human, Pig, Rabbit, Rat and Drosophila. Others not known.

Epitope: Not determined

Molecular Weight: ∽25kDa (predominant)

Positive Control: Ls174T cells, Tonsil

Cellular Localization: Nuclear Ab-1 recognizes cross-reactive epitopes on the B'/B and D polypeptides of Sm. Ab-1 precipitates the small nuclear RNAs U1, U2, U4, U5, and U6 providing direct evidence that the Sm antigen resides on all these RNA-protein complexes.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Affinity Purification
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

Especificaciones

Especificaciones

sm (Smith Antigen) Ab-1
Monoclonal
200μg/mL
Purified Ab with BSA and Azide
Murine
500μL
DNA Repair
Primary
Drosophila, Human, Porcine, Rabbit, Rat
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Y12
Unconjugated
Concentrated
IgG3 kappa
RUO
Primary
Monoclonal
Videos
SDS
Documentos
Certificados